What is biodegradable material
The term biodegradable is used to describe materials that decompose through the actions of bacteria, fungi, and other living organisms -simply put it has the ability to break down or decompose back into the natural environment without causing harm Examples of well known biodegradable materials used in medical industries are PLLA, PLGA, PGA, PDO and PCL
What is PLLA
Poly(L-lactide) is a biodegradable material with good bio-absorbability and bio-compatibility. After degradation in the body, PLLA products are excreted by metabolism and thus has no harmful side effects to the human body. It is for these reasons that PLLA products are currently widely used in the field of medicine, such as for one-time infusion equipment, medical surgical suture, drug delivery carriers, tissue engineering scaffolds, bone anchors, injectable microcapsules, microspheres, implants, elastomermaterials for organ support, etc.
-Polymer of Lactic acid
-Lactic acid -> CO2+ H2O
PLLA immune reaction
Some PLLA Eaten by macrophage
-By immune reaction activate fibroblast ro produce collagen The other PLLA remain in human body- half life 3years
Mechanism and technique - II
INJECTABLE POLY-L-LACTIC ACID POWDER
Reconstitute with 18ml of sterile water for injections
One vial contains Injectable PLLA 520mg
Made in Korea
This product is made from a mixture of PLLA powder FDA approved materials.
GANA FILL is more innovative and creative than all existing products.
It induces the formation of collagen which in turn has the effect of increasing volume of the part where the surgical procedure was done.
The augmentation will continue until the 8th week and will last for 2 years after the procedure.
Main areas of use are temple, cheek, This product uses the same main ingredients as Sculptra.
Reconstitute with distilled water
GANA FILL-X BODY
This GANAFILL X contains large amounts of PLLA 1560mg PLLA,
GANAFILL X is made for body augmentation. Breast ,hip, male and female genital organ.
Merits of GANAFILL VS fat implantation
1.Quicker dissolution time-under one hour
-If you have no time ,You can reconstitute water and shake well for 10minutes,
-if you use vortex mixer ,dissolution time will be under 60 seconds, shake 60seconds then just use it
3.Larger quantity.GANAFILL 520mg VS other PLLA fillers 150mg (GANAFILL X 1560mg)
4.Better contouring effect
-because GANAFILL has more PLLA
5.Less volume loss at first injection
-In a few days of sculptra injection. There will be no augmentation, You will see Initial volume loss, You have to wait 1-2months until
you see augmentation But GANAFILL has lower Volume loss
6.Low nodule formation- more water more dilution lower grnuloma
Merits of GANAFILL VS other PLLA fillers
1.Quicker procedure time under 1 hour
-Two or three GANAFILL are enough for full face augmentation
3.Faster recovery time under 2days
-Recovery time of fat implantation is over 1 month
Effect and Various application
-Breast and hip augmentation
-Hand and neck wrinkle improvement
-Female and male genital organ
-Vagina tightening and penis shaft thickening
1.Reconstitute with 18ml of sterile water at least 1hours before injection.
2.If you use vortex mixer ,dissolution time will be under 60 seconds.
3.Use blunt needle larger than 21G.
4.For subcutaneous injection. For better performance inject deeper.
5.Use fan technique and avoid injecting too much in one area.
6.Do not use for forehead, lips, nose or areas near the eyes.
7.Use for face, breast and hip volume augmentation and acne scar recovery.
8.Effects can be seen 4 weeks after treatment up until 8 weeks after treatment. Volume augmentation lasts for 2 years.
9.Vigorous massaging is necessary around the area of treatment for 30 minutes every day for the first week
10.Two or three session is needed
for full face
one vial is max
One month later
-half dose of first session
Depth of injection
-Subcutaneous layer or periosteum
-Fan technique using canula
1.Do not treatment prohibited area.(lip, nose, forehead)
2.Use distilled water only. (Do not use a saline solution or water.)
3.Don't inject at one spot too much , inject widely and deeply to avoid granuloma formation
4.Patient have to get second treatment.(Check progress)
|First session||Second session||Depth of injection||Injection technique|
|Temporal area||0.5Vial max||One month later half |
dose of first session
|Fan shape injection|
|Nasolabial fold||0.5Vial max |
|Cheek ||1Vial max |
|Ant zygomatic area||0.5Vial max |