GANA FILL ( PLLA filler)

What is biodegradable material
The term biodegradable is used to describe materials that decompose through the actions of bacteria, fungi, and other living organisms -simply put it has the ability to break down or decompose back into the natural environment without causing harm Examples of well known biodegradable materials used in medical industries are PLLA, PLGA, PGA, PDO and PCL


What is PLLA

Poly(L-lactide) is a biodegradable material with good bio-absorbability and bio-compatibility. After degradation in the body, PLLA products are excreted by metabolism and thus has no harmful side effects to the human body. It is for these reasons that PLLA products are currently widely used in the field of medicine, such as for one-time infusion equipment, medical surgical suture, drug delivery carriers, tissue engineering scaffolds, bone anchors, injectable microcapsules, microspheres, implants, elastomermaterials for organ support, etc.


Mechanism
-PLLA(Poly-L-lactic acid)
-Polymer of Lactic acid
-Lactic acid -> CO2+ H2O
 

PLLA immune reaction
Some PLLA Eaten by macrophage
 -By immune reaction activate fibroblast ro produce collagen The other PLLA remain in human body- half life 3years

Mechanism and technique - II
GANA FILL

INJECTABLE POLY-L-LACTIC ACID POWDER

Reconstitute with 18ml of sterile water for injections
One vial contains Injectable PLLA 520mg
Made in Korea  

GANA FILL-FACE

This product is made from a mixture of PLLA powder FDA approved materials.
GANA FILL is more innovative and creative than all existing products.
It induces the formation of collagen which in turn has the effect of increasing volume of the part where the surgical procedure was done.
The augmentation will continue until the 8th week and will last for 2 years after the procedure.
Main areas of use are temple, cheek, This product uses the same main ingredients as Sculptra.


Reconstitute with distilled water

Min 10cc
Max 18cc  

GANA FILL-X BODY

This GANAFILL X contains large amounts of PLLA 1560mg PLLA,
GANAFILL X is made for body augmentation. Breast ,hip, male and female genital organ.  

Merits of GANAFILL VS fat implantation

1.Quicker dissolution time-under one hour
-If you have no time ,You can reconstitute water and shake well for 10minutes,
-if you use vortex mixer ,dissolution time will be under 60 seconds, shake 60seconds then just use it
2.Cheaper price
3.Larger quantity.GANAFILL 520mg VS other PLLA fillers 150mg (GANAFILL X 1560mg)
4.Better contouring effect
-because GANAFILL has more PLLA
5.Less volume loss at first injection
-In a few days of sculptra injection. There will be no augmentation, You will see Initial volume loss, You have to wait 1-2months until
you see augmentation But GANAFILL has lower Volume loss
6.Low nodule formation- more water more dilution lower grnuloma


Merits of GANAFILL VS other PLLA fillers
1.Quicker procedure time under 1 hour
2.Cheaper price
-Two or three GANAFILL are enough for full face augmentation
3.Faster recovery time under 2days
-Recovery time of fat implantation is over 1 month


Effect and Various application
-Face augmentation
-Face lifting
-Breast and hip augmentation
-Hand and neck wrinkle improvement
-Scar improvement
-Female and male genital organ

-Vagina tightening and penis shaft thickening

Vortex mixer

GANAFILL PROCEDURE
1.Reconstitute with 18ml of sterile water at least 1hours before injection.
2.If you use vortex mixer ,dissolution time will be under 60 seconds.
3.Use blunt needle larger than 21G.
4.For subcutaneous injection. For better performance inject deeper.
5.Use fan technique and avoid injecting too much in one area.
6.Do not use for forehead, lips, nose or areas near the eyes.
7.Use for face, breast and hip volume augmentation and acne scar recovery.
8.Effects can be seen 4 weeks after treatment up until 8 weeks after treatment. Volume augmentation lasts for 2 years.
9.Vigorous massaging is necessary around the area of treatment for 30 minutes every day for the first week
10.Two or three session is needed

Face

First session
for full face
one vial is max

Second session
One month later
-half dose of first session

Depth of injection
-Subcutaneous layer or periosteum

Injection technique
-Fan technique using canula 

Precaution
1.Do not treatment prohibited area.(lip, nose, forehead)
2.Use distilled water only. (Do not use a saline solution or water.)
3.Don't inject at one spot too much , inject widely and deeply to avoid granuloma formation
4.Patient have to get second treatment.(Check progress)

 

First sessionSecond sessionDepth of injectionInjection technique
Temporal area0.5Vial maxOne month later half
dose of first session
Subcutaneous layer
or Periosteum
Fan shape injection
usingcannula
Nasolabial fold0.5Vial max
Cheek 1Vial max
Ant zygomatic area0.5Vial max