GANA PFS (peptide dermal filler)



GANA PFS

 ( Peptides+ dermal fillers)



Main indication

-Expression wrinkle removal
-Face lifting
-Wound repair
- Skin recover
-Fne wrinkle removal


Packaging unit

-Prefilled syringe 1.2 ml/ box

Ingredients

-Cross linked hyaluronic acid  20 mg/cc

-Acetyl hexa peptide -8

- Palmitoyl tetra peptide 7

- Palmitoyl pentapeptide 4

Precaution 

 Cause of acetyl hexa peptide -8
The some person might feel paralyzed facial expression
It is normal expectation
Reassure patients

 


Acetyl hexa peptide -8


is made up of peptides, which are chains of amino acids that can affect how cells in the body work.

 When Acetyl hexa peptide -8is applied to the skin, 
it is absorbed into the body and the cream's chemical composition 
causes the facial muscles to contract with less force.

Acetyl hexa peptide -8
prevents the formation of expression wrinkles by somehow inhibiting muscle movement. 

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Palmitoyl tetrapeptide-7 (Pal-GQPR) is



. (It was also formerly known and marketed as palmitoyl tetrapeptide-3.)
 Palmitoyl tetrapeptide-7 consists of a short chain of four amino acids (a.k.a. GQPR peptide or glycine-glutamine-proline-arginine) connected to palmitic acid. Palmitic acid is a fatty acid added to improve the peptide's oil solubility and thus skin penetration.
Palmitoyl tetrapeptide-7 is believed to work by reducing the production of interleukin-6 (IL-6) by the the key skin cells,
 keratinocytes and fibroblasts. 
IL-6 is a molecule that promotes inflammation, which, in turn, leads to faster degradation of the skin matrix and thus contributes to the development of wrinkles and loss of skin firmness and elasticity.
 By reducing the levels of IL-6 and possibly other inflammation mediators, palmitoyl tetrapeptide-7 is thought to slow down the degradation of the skin matrix and may also stimulate its replenishment.

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Palmitoyl Pentapeptide-4
 


Pentapeptide-4 activates certain genes involved in the process of extracellular matrix renewal and cell proliferation. 
Its 16-carbon aliphatic chain is for improving the penetration of the molecule through the lipid structures of the skin.
Stimulates collagen I, III and VI fibronectin, elastin, glucosamnoglycans production.

 

Palmitoyl Pentapeptide is a compound that is derived from a five-part chain of amino acids known as pro-collagen I pentapeptide. 
By itself, this amino chain has been shown to increase the production of collagen in laboratory cultures.
 Palmitoyl pentapeptide is a synthetic derivative of this five-part amino acid chain, and it is normally marketed under the brand name Matrixyl, which is simply a combination of palmitic acids and amino-acid chains.
Functionally, Palmitoyl Pentapeptide promotes the production of two compounds: collagen and hyaluronic acid.Combined, 
these compounds help the skin recover and heal from wounds and penetrative damage by generating new specialized skin cells that bind the damaged tissue together.